L-carnitine Reduces Muscle Cramps in Patients With Cirrhosis posted on April 6, 2015 cirrhosisL-Carnitineliver diseasemuscle cramps Share this Post Share on Twitter Share on Facebook Share on Google Plus April 6, 2015 This December 9, 2014 article from Clinical Gastroenterology Hepatology evaluated a prospective study to evaluate L-carnitine, which is involved in the beta-oxidation of fatty acids, to reduce muscle cramps in patients with cirrhosis. They were given L-carnitine 300mg, 3 times a day or 4 times a day for 8 weeks. Muscle cramps were decreased by 43.5% in the 4 time a day dosing vs improvement of 10.5% in the 3 times a day dosing. No adverse events were reported. It appears that L-carnitine is safe and effective for reducing muscle cramps in patients with cirrhosis. Here is the link to the entire article: L-Carnitine Effectively Reduces Muscle Cramps in Patients with Cirrhosis God bless you and to your good health! Joyce Gibb MS, CRNP Ask The Pharmacist Group, LLC Liver Essentials Plus (60) $48.99 Add to cart No ratings. L-Carnitine 500 mg (60) $30.99 Add to cart No ratings.