Product Details (Formerly WholeMune, an Ortho Molecular Product) Core-Immune Essentials is formulated with Wellmune WGP®, the most well-researched, single beta-glucan, proven in clinical trials to prepare and protect the immune system from repeated and ongoing stressors. Wellmune® WGP is a highly purified, yeast-free beta-glucan extract derived from Saccharomyces cerevisiae; it is standardized to contain 75% pure beta-glucan and is considered to be the most effective single nutrient to naturally prime immune cells to enhance immune function. Why These Natural Ingredients? A strong immune system is integral to overall health and wellbeing. Maintaining a strong immune system can often be a challenge in today’s world- high stress levels, poor diet, lack of sleep and environmental pollutants can all slow down the immune response. Core-Immune Essentials primary active ingredient is Wellmune WGP®- a natural beta 1,3/1,6 glucan derived from the cell wall of a proprietary strain of baker’s yeast (Saccharomyces cerevisiae). Once swallowed, immune cells in the gastrointestinal tract take up Wellmune WGP® and transport it to immune organs throughout the body. Specific immune cells called macrophages digest Wellmune WGP® into smaller fragments and slowly release them over a number of days. The fragments then bind to neutrophils (white blood cells), via complement receptor 3 (CR3). Neutrophils are the most abundant immune cells in the body, accounting for 60-70% of all immune cells. The activation of neurotrophils by Wellmune WGP® fragments allows these cells to move faster throughout the body, resulting in a significant boost in immune defense.