OSTEO GUARD ® PLUS IPRIFLAVONE

Description

Osteo-guard® Plus Ipriflavone, provided by Douglas Laboratories®, combines ipriflavone, a flavonoid
isoflavone, with calcium from microcrystalline calcium hydroxyapatite compound (MCHC) prepared from whole
bovine bone, and magnesium from an amino acid complex. Osteo-guard® Plus Ipriflavone also provides
phosphorus trace minerals, bone matrix proteins, amino acids, and glycosaminoglycans in their natural forms.

FUNCTIONS
Bone is constantly turning over, a continuous process of formation and resorption. In normal aging, there is a
gradual loss of bone. Ipriflavone helps promote bone density by inhibiting bone resorption.† Numerous studies
of postmenopausal women and individuals whose bones are showing signs of demineralization have
investigated the benefits of ipriflavone on bone health. Laboratory and clinical studies have documented
ipriflavone’s positive effect on bone density. †
Osteoclasts and osteoblasts are two primary types of bone cells. Osteoblasts, the more exterior cells, are
responsible for bone mineralization. Osteoclasts, found beneath the osteoblasts, are responsible for bone
resorption. Experts agree that ipriflavone appears to directly inhibit osteoclast activity, thereby decreasing bone
resorption. † Scientists suspect ipriflavone may also stimulate osteoblast activity. † Since osteoblasts are
responsible for laying down new bone, an increase in osteoblast activity may result in increased bone
mineralization. This suggests Ipriflavone may not only inhibit the breakdown of existing bone, but also
encourage the formation of new bone. †
In women, bone loss is generally accelerated following menopause. Ipriflavone, together with adequate
calcium, vitamin D, vitamin K, and other key nutrients involved in bone health, offers non-estrogenic protection
against excessive bone resorption.† Unlike other well-known isoflavones, such as genistein found in soy foods,
ipriflavone does not have estrogenic activity and can be safely used in conjunction with natural phytoestrogens
or with hormone replacement therapy (HRT).

INDICATIONS
Osteo-guard® Plus Ipriflavone may be a useful dietary supplement for anyone who wishes to increase their
intake of calcium, magnesium and other nutritional factors for maintaining good bone health.

FORMULA (#OSG-IP)
Two tablets contain:
Calcium (microcrystalline
Hydroxyapatite) ……………………………………………………..300 mg
Phosphorus (microcrystalline
Hydroxyapatite) ……………………………………………………..144 mg
Magnesium (amino acid chelate/oxide complex)………..125 mg
Ipriflavone……………………………………………………………..300 mg
Vitamin D3 (cholecalciferol)……………………………………..200 I.U.
Vitamin K1 (phytonadione)………………………………………100 mcg
Boron (aspartate-citrate) …………………………………………0.25 mg
Other ingredients: Cellulose, calcium carbonate, dicalcium
phosphate, croscarmellose sodium, vegetable stearate,
silica, Coating ingredients: water, polyethylene glycol, magnesium silicate, (poly)
ethenol, and polysorbate 80

SUGGESTED USE
Adults take two tablets daily with food or as directed by a healthcare professional.

STORAGE
Store in a cool, dry place, away from direct light. Keep out of reach of children.

† These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.