Mucosagen Capsules 180

Description

FORMERLY MUCOSAL ESSENTIALS-SAME PRODUCT DOSE AND PRICE-JUST A NEW NAME AND LABEL

Mucosagen incorporates ingredients that help support a healthy gastrointestinal tract.

Why These Natural Ingredients

Gut Wall Support 

The presence of glutamine in the diet supports healthy intestinal lining which may limit the amount of endotoxins allowed through the gut wall. (Also aiding is N-Acetyl D-Glucosamine.) 

Liver Support 

The presence of silymarin (milk thistle) and NAC supports optimal liver function.

This product is a comprehensive formula designed to help support barrier function of the gastrointestinal GI lining. The mucosal epithelium serves multiple purposes including
allowing nutrients from the diet to be absorbed and digested while simultaneously serving as a barrier that protects against unwanted food particles, toxins and microorganisms
from passing directly into the body. This product contains a synergistic blend of ingredients that support the health of the GI lining while promoting inflammatory balance and
liver detoxification pathways to support overall health.

Overview

Under healthy conditions, the GI tract contains a semipermeable epithelial mucosal barrier which protects against the unwanted passage of food antigens, toxins, and
microorganisms from crossing directly into the bloodstream. Several factors can affect the integrity of the epithelial barrier including medications (particularly NSAIDs) non-steroidal
anti-inflammatory drugs), stress, alcohol intake, injury, trauma, microbial imbalance and poor nutrition. Reducing the impact of these factors and preserving a healthy GI tract is critical for
maintaining long term health. In order to protect the mucosal barrier, a thick, complex layer of mucus is produced. From the stomach and throughout the
intestines, the mucosa consists of a single layer of epithelial cells covered by a layer of secreted mucus. Like saliva, mucus is a complex fluid that is rich in mucin glycoproteins . Mucin
shields epithelial tissue from mechanical and chemical stress. Mucin also provides a broad range of immune support which helps maintain microbial balance.
This product contains L-glutamine, gamma oryzanol, N-acetyl D-glucosamine and lactoferrin to help support the health of the inetstinal mucosal barrier and maintain healthy mucin
production. This product also includes the additional benefit of N-acetyl cysteine and milk thistle to promote detoxification of harmful chemicals.

L-Glutamine

L-glutamine is an amino acid which serves as a primary source of fuel for the small intestines. Epithelial cells in the smallintestines (enterocytes) use L-glutamine as their metabolic
fuel which helps maintain mucosal growth, structure, and function. [1] Under times of stress, L-glutamine has been shown to become a conditionally essential amino acid, helping
to regenerate and maintain a healthy mucosal barrier.[2] An increase in intestinal permeability can result in increased exposure to food, toxins and microorganisms. Inflammatory
signals that are released during this exposure can trigger the stress hormone cortisol to increase the breakdown and utilization of L-glutamine in the small intestines. [3] L-glutamine
provides the primary fuel source for the gut mucosal lining to maintain the health of gut tissue. [3]

Gamma Oryzanol

Gamma oryzanol is a natural component of rice bran oil. It is a mixture of ferulic acid esters of sterol and triterpene alcohols. Rice bran oil contains about 1-2% gamma oryzanol where
it functions as a highly effective antioxidant in the GI tract. Gamma oryzanol has been shown to protect gastric mucosa from free radical stress and promote inflammatory balance by
inhibiting NFkB in macrophages. [4,5] N-Acetyl-Glucosamine† N-acetyl glucosamine is the acetylated form of glucosamine. N-acetyl glucosamine is a mucin precursor and has been
shown to increase the production of mucus within the GI tract. [6] Colonic mucus production has been shown to be deficientin individuals with GI challenges. Research has indicated that
the step involving N-acetylation of glucosamine is deficient in patients with intestinal challenges. [7-8] This can result in a decrease of glycoproteins that protect the intestinal mucosa. [8]

CLINICAL APPLICATIONS

• Supports G.I. Barrier Health
• Boosts Liver Function and Detoxification Pathways
• Promotes Inflammatory Balance and Mucin Production in the G.I. tract

This statement has not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure, or prevent any disease.

Lactoferrin

Lactoferrin is a glycoprotein that is naturally found in colostrum, a milky fluid produced by the mammary glands. Lactoferrin plays a major role in supporting immune health including
both innate and adaptive immune functions. Lactoferrin helps support microbial and inflammatory balance. [9] In animal studies, orally administered lactoferrin supported the health
of the GI tract in mice, and provided protection against NSAID activity. [10] Research has also indicated that lactoferrin can help
support inflammatory balance in the gut by inhibiting TNFα and promoting cytokine IL-8. [10] Silymarin (Milk Thistle Seed Extract) †
Milk thistle (Silybum marianum) is an annual plant indigenous to Europe and the United States and has been used for centuries as an herbal medicine to support liver health. The extract of milk thistle has silymarin, the biologically active component found in the seeds and leaves of this plant. Silymarin provides liverprotective effects via several mechanisms of action, including
inhibiting lipid peroxidation; [11] supporting liver detoxification through enhancement of the liver’s glucuronidation pathways; [12] and protection against glutathione depletion.[13] Silymarin
has been shown to increase hepatocyte protein synthesis resulting in hepatic tissue function. [14]

N-Acetyl-L-Cysteine

N-acetyl cysteine (NAC) is a sulfyhydryl containing amino acid that is commonly used to support liver and gut health. NAC is an effective precursor to the major antioxidant in the
body, glutathione. Oral supplementation with NAC has been shown to increase intracellular glutathione levels. [15] NAC also stimulates a specific detoxification pathway in the liver called
glutathione conjugation. [16]

Micronutrient Blend

This product contains the synergistic nutrient combination of zinc, vitamin A, and biotin, which are crucial form maintaining GI health. Zinc is an essential mineral that is widely recognized
for its role in gut and immune health. Zinc has been shown to strengthen GI barrier function by supporting the structure of tight junctions. [16] Vitamin A is crucial for supporting GI
integrity, promoting inflammatory balance by reducing NFkB, and supporting mucus production. [17] Biotin is an essential
nutrient that is produced by several species of intestinal bacteria. Biotin deficiency is often present in individuals with G.I. challenges. [18]

Directions

2 capsules three times per day or as recommended by your health care professional.
Does Not Contain Gluten, corn, yeast, artificial colors and flavors.
Cautions: If you are pregnant or nursing, consult your physician before taking this product.